![]() We hope this Review serves not only to inform but also to encourage readers to incorporate some of these techniques into their own research and to take advantage of the worm research community’s culture of openness in the sharing of resources, protocols and reagents. In this Review, we discuss selected examples of these new developments. elegans to study a wider range of biological processes ( TABLE 1). In the past few years, several technological advances have allowed greater ease in manipulating the worm for existing applications, as well as providing new opportunities for using C. For example, even though the worm genome is 30-fold smaller than the human genome, it contains almost as many genes 4, and most of these have human homologues 5. Despite its simplicity, studies in the worm also provide broader implications for fields such as biomedical research. It was the first multicellular organism to be sequenced 4, and worm researchers were early adopters of genomic methods, such as microarrays. ![]() ![]() As a simple organism, the worm is an ideal platform for implementing new technologies. ![]() elegans has provided fundamental advances in our knowledge of several biological processes, including development, apoptosis, neurobiology, gene regulation and ageing. The nematode worm Caenorhabditis elegans has many features that make it an attractive model organism, including a defined, invariant cell lineage 1– 3 and extensive genetic tools. ![]()
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